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Class: HIV protease inhibitor PI ; Standard dose: Two 200 mg capsules once daily, take with food. Treatment-experienced people should take 300 mg with 100 mg Norvir once daily. Also available in 100 mg and 150 mg capsules. Take missed dose as soon as possible, but do not double up on your next dose. AWP: $892.91 for 200 mg, 60 capsules Manufacturer contact: Bristol-Myers Squibb, reyataz , 1 800 ; 2724878 AIDS Treatment Information Service: 1 800 ; HIV0440 4480440 ; Potential side effects and toxicity: Most common include: dizziness and lightheadedness. Elevated levels of unconjugated bilirubin produced by the liver ; was reported in clinical trials in some individuals taking Reyataz. This may result in cases of jaundice yellowing of the skin or eyes, darkening of the urine, or itching skin ; , reported in 79% of individuals taking Reyataz. However, no evidence of hepatoxicity liver problems ; was reported. These symptoms usually go away after about two weeks or after you stop taking Reyataz, and seldom return on re-initiation. All other protease inhibitors are associated with increased levels of cholesterol and triglycerides, except possibly unboosted Reyataz and these increased levels may be associated with heart disease. However, if Reyataz is boosted with Norvir these same changes in cholesterol and triglycerides may occur. Other possible side effects as seen in other PIs are lipodystrophy body fat changes, including thinning of the face, arms and legs, with or without fat accumulation in the stomach, breasts and sometimes the upper back ; , onset of new cases or worsening of diabetes see your doctor promptly ; and increased bleeding in hemophiliacs. Potential drug interactions: Do not take with proton pump inhibitors PPIs--long-acting medicine for acid reflux ; : Prilosec-OTC, Prevacid, Axiphex or Nexium. May be taken 12 hours apart from short-acting acid reflux medications H2 inhibitors or blockers ; like Zantac and Axid. Antacids like Mylanta must be taken at least two hours apart from Reyataz. Must be taken two hours apart from Videx, due to Videx's buffer, and must take Videx-EC an hour before or two hours after Reyataz, due to food restrictions unless taking VidexEC with Viread ; . Boost with Norvir 300 mg Reyataz with 100 mg Norvir ; when taking in combination with Sustiva. Viread decreases the concentration levels of Reyataz. In addition, Reyataz increases Viread concentrations. Higher Viread concentrations could increase Viread-associated adverse events, including renal disorders. The FDA suggests those receiving Reyataz and Viread should be monitored for Viread-associated adverse events. When co-administered with Viread, it is recommended that Reyataz 300 mg is given with Norvir 100 mg all as a single daily dose with food ; . Reyataz without Norvir should not be taken with Viread. Do not take with Tambocor, Rythmol, Versed, Halcion, Hismanol, Seldane, rifampin, ergot derivatives such as Cafergot, Wigraine and Methergine, D.H.E. 45, in any form--serious interactions seen with dilation during gynecological exams ; , garlic supplements, and the herb St. John's wort. Reduce dose and frequency of rifabutin to 150 mg once a day. Do not use Zocor or Mevacor; lipid-lowering alternatives are Lipitor, Lescol, and Pravachol, but they should be used with caution due to potential for liver toxicity. Protease inhibitors increase blood levels of Viagra, Cialis and Levitra. Use with caution. Initially the Viagra dose. Facilitator Briefing: The sale of ice generates a lot of money. As you watch the film, take notes on the costs of illegal drugs on the streets. Prompts: How much does a gram of ice cost on the street? How much ice is used in Hawaii? Reflection Questions: Why is it a problem that money generated by ice doesn't stay in the state? What would you buy with the money a typical user spends on ice? Why do some ice users turn to crime? and altace. Drugs designed to lower the elevations in bp with hypertension can have diminished effectiveness if taken along with licorice.
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D43 - Travel and migration, immigration CDD1123 - Access to treatment myths or difficulties for HIV-infected child in ethnic minority groups S. Sripunya AIDS ACCESS Foundation, Chiangrai, Thailand Issues: Chiangrai is the top north province in Thailand and has its border near Mynmar & Lao PDR. Among 12% of 1.2 million people is ethnic minority, who lives in the hilltribe area and there are much more than 20 ethnic groups so that the culture and langauge are different. Therefore, there are many obstacles for access to treatment such as language barrier, lack of the information on the health care system, lack of knowledge about HIV AIDS including both care and treatment, living far away, stigma and discrimination, illegal drug, poverty, especially on attitude and religion barrier. Then, it is very difficult for these HIV + children and their family could assess for HIV AIDS treatment. Description: AIDS ACCESS Foundation is Thai NGO established in 1991, started campaign Access to treatment and cooperated with Chiangrai Provincial Hospital in early 2002 from 8 children. Up until now this campaign could help to provide ARV treatment for 300 HIV + children and 30 cases is ethnic children who lack of legel nationality. We found that their adherence is more than 95%. This support including preparation, home visit, counseling, day care and economy support for children and families. Lessons learned: Making connection with local GOs, CBOs and NGOs could help to provide home base care for HIV + children and there families. Psycho-social support and economic assistance are necessary for children and families to keep adherence and to improve quality of live as same as medical care. Recommendations: To promote Access to Treatment among HIV + children among ethnic minorities need to be strenghthen by the collaboration with GOs, CBOs, health care workers, PHA group leaders, provincial and community hospitals, villagers and local NGOs. Advocacy and policy involvement is necessary to be concerned.

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