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Further references beer's criteria for potentially inappropriate medication use in the elderly by sheila molony - from the try this series. 31 66. Niederau C, Faber S, Karaus M. Cholecystokinin's role in regulation of colonic motility in health and in irritable bowel syndrome. Gastroenterology 1992; 102: 18891898. O'Brien MD, Camilleri M, Thomforde GM, Wiste JA, Hanson RB, Zinsmeister AR. Effect of cholecystokinin octapeptide and atropine on human colonic motility, tone, and transit. Dig Dis Sci 1997; 42: 2633. Bampton PA, Kinning PG, Kennedy ML, Lubowski DZ, deCarle D, Cook IJ. Spatial and temporal organization of pressure patterns throughout the unprepared colon during spontaneous defecation. J Gastroenterol 2000; 95: 10271035. Kamm MA, van der Sup JR, Lennard-Jones JE. Colorectal and anal motility during defecation. Lancet 1992; 339: 820. Karaus M, Sarna SK. Giant migrating contractions during defecation in the dog colon. Gastroenterology 1987; 92: 925933. Lubowski DZ, Meagher AP, Smart RC, et al. Scintigraphic assessment of colonic function during defecation. Int J Colorectal Dis 1995; 10: 9193. Hardcastle JD, Mann CV. Study of large bowel peristalsis. Gut 1968; 9: 512520. Hardcastle JD, Mann CV. Physical factors in the stimulation of colonic peristalsis. Gut 1970; 11: 4146. ParkmanHP, Ma RC, Stapelfeldt WH, Szurszewski JH. Direct and indirect mechanosensory pathways from the colon to the inferior mesenteric ganglion. J Physiol 1993; 265: G499G505. 75. Ganong WF. Cutaneous, deep, and visceral sensation. In: Ganong WF, ed. Review of Medical Physiology. 10th ed. Los Altos, CA: Lange Medical Publishers; 1981: 97106. 76. Ganong WF. The reticular activating system, sleep, and the electrical activity of the brain. In: Ganong WF, ed. Review of Medical Physiology. 10th ed. Los Altos, CA: Lange Medical Publishers; 1981: 144153. 77. Haack VS, Chesters JG, Vollendorf NW, Story JA, Marlett JA. Increasing amounts of dietary fiber provided by food normalizes physiologic response of the large bowel without altering calcium balance or fecal steroid excretion. J Clin Nutr 1998; 68: 615622. Harvey RF, Pamare EW, Heaton KW. Effects of increased dietary fibre on intestinal transit time. Lancet 1973; 1: 12781280. Pilch SM, ed. Physiological Effects and Health Consequences of Dietary Fiber. Bethesda, MD: Life Sciences Research Office, Federation of American Societies for Experimental Biology; 1987. 80. Chen HL, Haack VS, Janecky CW, Vollendorf NW, Marlett JA. Mechanisms by which wheat bran and oat bran increase stool weight in humans. J Clin Nutr 1998; 68: 711719. Moses FM. Effect of moderate exercise on the gastrointestinal tract. Sports Med 1990; 9: 159172. Riddoch C, Trinick T. Prevalence of running-induced gastrointestinal GI ; disturbances in marathon runners. Br J Sports Med 1998; 22: 7174. Krevsky B, Maurer AH, Fisher RS. Patterns of colonic transit in chronic idiopathic constipation. J Gastroenterol 1989; 84: 127132. Hutchinson R, Notghi A, Harding LK, et al. Scintigraphic measurement of ileocecal transit in irritable bowel syndrome and chronic idiopathic constipation. Gut 1995; 36: 585589. Pemberton JH, Rath DM, Ilstrup DM. Evaluation and surgical treatment of severe chronic constipation. Ann Surg 1991; 214: 403411 and hydrochlorothiazide. 2472 LASER PHOTOCOAGULATION TREATMENT FOR DIABETIC MACULAR EDEMA AND ITS EFFECT ON PATIENT S VISION-RELATED QUALITY OF LIFE TRANOS P 1 ; , TOPOUZIS F 2 ; , HARRIS M 1 ; , DAVEY C 1 ; , CHAN J 1 ; , DIMITRAKOS S 2 ; , STANGOS N 2 ; 1 ; Royal Free Hospital, London, UK 2 ; AHEPA General Hospital, Thessaloniki, Greece Purpose: To evaluate the effect of laser photocoagulation for diabetic macular edema DME ; on patients' Vision Related Quality Of Life VR-QOL ; . Methods: The study cohort was composed of 44 subjects with mean age of 64.7 9.79 years who underwent laser treatment for DME. Eligible patients with no history of previous laser treatment for diabetic retinopathy DR ; completed a vision targeted survey 51 item National Eye Institute Visual function questionnaire ; prior treatment and 3 months following the last session of laser application. Multi-item scales rating different aspects of VR-QOL were compared prior and after photocoagulation. Age matched individuals with DR who did not require laser treatment were enrolled in a reference sample. Results: Scale scores associated with general vision , near and distance vision were higher following laser treatment p 0.012, p 0.05 and p 0.01 respectively ; . Similar improvement was observed in vision specific social functioning p 0.006 ; and in patients' emotional well being p 0.01 ; . Scale scores for subjects' expectations of visual function and dependency due to vision were improved after photocoagulation but failed to reach statistical significance. In contrast items assessing general health revealed trend to deterioration over the time of the study. Conclusion: Photocoagulation for DME has beneficial effect on patients' capability in performing daily visual tasks. Application of laser treatment is associated with improved VRQOL and better emotional status and social functioning. 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Reference Title Inclusion or exclusion Included 36 Senni, M., Rodeheffer, R. J., Tribouilloy, C. M., Evans, J. M., Jacobsen, S. J., Bailey, K. R., & Redfield, M. M. 1999, "Use of echocardiography in the management of congestive heart failure in the community", Journal of the American College of Cardiology, vol. 33, no. 1, pp. 164-170. Shamim, W., Francis, D. P., Yousufuddin, M., Varney, S., Pieopli, Not relevant outcome M. F., Anker, S. D., & Coats, A. J. 1999, "Intraventricular conduction delay: a prognostic marker in chronic heart failure", International Journal of Cardiology, vol. 70, no. 2, pp. 171-178. 20 34 Shamsham, F. & Mitchell, J. 2000, "Essentials of the diagnosis of Included heart failure. [Review] [36 refs]", American Family Physician, vol. 61, no. 5, pp. 1319-1328. Smith, H., Pickering, R. M., Struthers, A., Simpson, I., & Mant, D. Included 2000, "Biochemical diagnosis of ventricular dysfunction in elderly patients in general practice: observational study. [see comments]", BMJ, vol. 320, no. 7239, pp. 906-908. Tan, L. B. 1991, "Evaluation of cardiac dysfunction, cardiac reserve and inotropic response", Postgraduate Medical Journal, vol. 67, no. Suppl 1, p. S10-S20. Tan, L. B. 1995, "The assessment of cardiac performance, " in Applied physiology for surgery and critical care, M. A. Glasby & C. L. H. Huang, eds., Butterworth-Heinemann, Oxford, pp. 160-169. Tan, L. B., Cooke, G. A., & Cubukcu, A. 1994, "How to investigate Heart Failure", British Journal of Cardiology, vol. 1 and 2, pp. 305, 333-308, 336. Tan, L. B., Mills, J., & Wright, D. J. 1999, "Management of heart failure", Journal of the Royal College of Physicians of London, vol. 33, no. 1, pp. 25-30. Tan, L. B., Wright, D. J., Marshall, P., & Riley, R. 1997, "Is exercise capacity a reiable indicator for diagnosis and treatment of Heart Failure", International Proceedings Journal, vol. 9, no. 1, pp. 13-29. Tresch, D. D. 1997, "The clinical diagnosis of heart failure in older patients. [see comments]. [Review] [38 refs]", Journal of the American Geriatrics Society, vol. 45, no. 9, pp. 1128-1133. Not relevant outcome Not relevant outcome Included Not relevant outcome Not relevant outcome. View this table table current medical and psychological behavioral treatment options conclusion irritable bowel syndrome is one of the most frequently diagnosed disorders in the general population. Glucophage continued: page 2 add this article to your favorites email this article print this article other articles in this emedtv presentation glucophage side effects glucophage and weight loss what is glucophage used for.

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