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Citation journal of community health nursing 1986, vol, for example, canon image prograf ipf5000.
Pharmacokinetic data indicate that whole blood concentrations rather than plasma concentrations serve as the more appropriate sampling compartment to describe prograf tacrolimus pharmacokinetics.
Ation Set HEDIS ; . Compounding the delicacy of managing disparate drug formularies and attempting to structure health care dellivery through practice guidelines is the, for example, canon prograf printer.
Study design flawed. * Francis Severity IBS Score. B. bifidobacterium, D-IBS diarrhea-predominant irritable bowel syndrome, ITT intention to treat, L. lactobacillus, N number of patients, NS non-significant, P. Propionibacterium, S. Saccharomyces.
Piscitelli sc, flexner c, minor jr, polis ma, masur drug interactions in patients infected with human immunodeficiency virus and tacrolimus.
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Stedim sted im ; provides the industry with further information on extractable and leachable interaction studies, protein adsorption studies, and chemical resistance studies. Extractables and Leachables Model solvent extraction tests were conducted to generate extractables leachables from containers using low, neutral, and high pH solutions, as well as pure ethanol. Extracts were identified and quantified using a purge-and-trap method.
Or click the first letter of a drug name: a b c advanced search drugs & medications diseases & conditions pharmaceutical news & articles pill identifier drug interactions checker medical encyclopedia medical dictionary community forums welcome guest register or sign in my viewing history my drug list my interactions lists member offers search results for: prograf refine results for prograf : drug images or click to enlarge and pantoprazole.
Star device were used: generation I in 14% n 38 ; , generation II in 27% n 74 ; and generation III in 59% n 164 ; of the patients. The sizes of the devices were 18 mm n 139 ; and 35 mm n Trans-septal puncture was necessary in one patient because of the short distance of the PFO channel to the anterior mitral valve leaflet. Procedural time ranged from 9 to 48 min mean: 24 8 min ; , with fluoroscopy times of 1.4 to 10.2 min mean: 4.1 2.3 min ; . Peri-interventional complications within 24 h ; . Device implantation was performed successfully in all patients. The overall peri-interventional complication rate was 4% 11 of 276 patients most complications were minor and all were reversible Table 2, upper part ; . Four patients developed transient ST-segment elevations in the inferior leads, presumably due to air embolism through the trans-septal sheath during device delivery or to mechanically induced spasm of the coronary arteries. The ECG changes resolved within 3 min. In one patient an additional reversible atrioventricular block III developed, with a slow ventricular escape rhythm requiring temporary pacing. In two patients a reversible peri-interventional TIA was observed. One of these patients suffered a right arm paresis, the other a mild left hemiparesis. These neurologic symptoms completely resolved within 4 h. No irreversible cerebral or peripheral ischemic events related to the implantation procedure occurred. Most complications were observed in the early phase of the study, likely because of the original cumbersome underwater introduction system, which may have produced embolization of small air bubbles. After the introduction system was changed to a more practicable and safer highpressure flushing-loading system, and additionally through the learning curve of the physicians, peri-interventional complications were significantly reduced. Major complications occurred in 2 of 276 patients 0.8% ; . In one patient, a 30-mm generation II device embolized in the systemic circulation and was successfully removed with a snare from the bifurcation of the aorta. Dislodgement of the device into the proximal orifice of the PFO channel after the device was released from guidewire forceps has been observed in another patient, who had a relatively long PFO channel. According to repetitive TEEs the position of the device was.
| What is prografI read the article in wired and it appears that starzl has something going - i believe he's talking about reducing things like cyclosporine, prograf, maybe immuran, i don't know about prednisone specifically and pentoxifylline!
Because of this potential risk of anaphylaxis, prograf injection should be reserved for patients who are unable to take prograf capsules.
What your thoughts on this new preventive medication and trental.
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DISCUSSION It was the goal of this study to see whether the inhibition of lung ion transport by hypoxia, which has been observed in native rat lung 8 in primary and SV-40 transformed alveolar type II cells as well as in A549 cells, a human lung derived adenocarcinoma cell line with characteristics of alveolar type II cells 19, is an adequate mechanism to conserve energy during hypoxia and which other mechanisms might also decrease ATP-demand. The major finding of this study is that alveolar epithelial cells in fact decrease their oxygen consumption rapidly upon exposure to hypoxia which can be interpreted as an adaptive mechanism to conserve energy in a situation of reduced oxygen availability. In A549 cells, this is in part due to a reduced proportion of oxygen consumption attributable to a reduced activity of the Na KATPase, of protein synthesis and of other metabolic pathways that have not been identified in this study, and might also be caused by inhibition of mitochondrial respiration. However, inhibitors of ion transport pathways that mediate secondary active Na-entry into the cell do not affect cellular oxygen consumption. A possible limitation of this study needs to be addressed. Inhibition of ion transport activity, transport protein expression, protein synthesis and ATP-production by hypoxia has been observed on lung tissues of different origin and primary rat alveolar epithelial cells, but also in the A549 tumor derived cell line. It needs to be pointed out, however, that tumor cells are particularly resistant to hypoxia for review see e.g. 25 ; . Though the pattern of adjustments of A549 tumor cells to hypoxia appears similar to that observed in native tissue, it remains to be clarified whether the restriction by hypoxia of metabolic activity and mitochondrial function observed on A549 cells justifies any generalization on specific adaptive mechanisms of alveolar epithelial cell or on lung function in clinical situations that cause alveolar hypoxia. The results on primary rat alveolar type II cells indicating a hypoxia-induced inhibition of JO2, tot may point towards the validity of such conclusion.
Tacrolimus is commercially available by fujisawa as the immunosuppressant prograf r ; and protopic r ; for the treatment of atopic dermatitis, respectively and
pheniramine.
Amphotericin B, and cisplatin. Initial clinical experience with the coadministration of Prkgraf and cyclosporine resulted in additive synergistic nephrotoxicity. Patients switched from cyclosporine to Pdograf should receive the first Pograf dose no sooner than 24 hours after the last cyclosporine dose. Dosing may be further delayed in the presence of elevated cyclosporine levels. Drugs that May Alter Tacrolimus Concentrations Since tacrolimus is metabolized mainly by the CYP3A enzyme systems, substances known to inhibit these enzymes may decrease the metabolism or increase bioavailability of tacrolimus as indicated by increased whole blood or plasma concentrations. Drugs known to induce these enzyme systems may result in an increased metabolism of tacrolimus or decreased bioavailability as indicated by decreased whole blood or plasma concentrations. Monitoring of blood concentrations and appropriate dosage adjustments are essential when such drugs are used concomitantly. * Drugs That May Increase Tacrolimus Blood Concentrations Calcium Channel Blockers diltiazem nicardipine nifedipine verapamil Antifungal Agents clotrimazole fluconazole itraconazole ketoconazole * voriconazole Macrolide Antibiotics clarithromycin erythromycin troleandomycin.
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To the formulary for supportive treatment in surgery for improvement of haemostasis where standard techniques are insufficient. Absorbable haemostats available are not listed in the formulary. Tacrolimus is on the Fife Formulary. The indication for tacrolimus Orograf ; for the prophylaxis of transplant rejection in heart allograft recipients would be following initiation by transplant centres. deferasirox Exjade ; was not added to the formulary for the treatment of chronic iron overload associated with the treatment of rare acquired or inherited anaemias requiring recurrent blood transfusions. It is not recommended for patients with myelodysplastic syndromes which constitute the largest group of patients in Scotland with transfusion-dependent anaemias and these patients were not included in the pivotal trial. propiverine hydrochloride 30 mg modified release capsule Detrunorm XL ; was not added to the formulary for the treatment of urinary incontinence, as well as urgency and frequency in patients who have idiopathic detrusor overactivity overactive bladder ; . The medicine is non formulary and formulary options of tolterodine XL 1st choice ; , oxybutynin and solifenacin should be used in preference. Rituximab Mabthera ; for use in combination with methotrexate for the treatment of adults with severe active rheumatoid arthritis, who have had an inadequate response or are intolerant to other disease modifying drugs including one or more tumour necrosing factor inhibitors was added to the formulary for specialist initiation only. Tirofiban Aggrastat ; was added to the formulary for specialist use only for the prevention of early myocardial infarction in patients presenting with unstable angina or nonQ-wave myocardial infarction with the last episode of chest pain occurring within 12 hours and with ECG changes and or elevated cardiac enzymes.
Does your skin appear fragile or burn easily? YES NO If yes, explain: Do you have trouble healing from a cut or burn? YES NO If yes, explain: Do you have any health problems? YES NO If yes, explain: Do you ever use depilatories or waxes on your face? YES NO How often? and
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In their zeal to remain competitive, a number of companies have attempted to expand this protection. Recently, a number of cases revealing serious and significant abuses have come to light. A number of the methods that have been employed by some drug companies both brand and generic ; have raised the ire and concern of members of Congress, consumer groups, health insurers, state attorneys general, and the Federal Trade Commission FTC ; .16 These concerns have lead to suits, charges, and efforts by some to modernize Hatch-Waxman.
507 2001 Community outreach initiative for the influenza vaccine vs. No new outreach program in persons aged 65 years old and older not vaccinated for influenza in the last year Trimethoprim-Sulfamethoxazole prophylaxis for pneumocystic carinii pneumonia PCP ; with discontinuation if adverse drug reaction occurs vs. No pneumocystic carinii pneumonia PCP ; prophylaxis in patients with Wegener's Granulomatosis receiving immune suppressant therapy Trimethoprim-Sulfamethoxazole prophylaxis for pneumocystic carinii pneumonia PCP ; with switch to aerosolized pentamidine if adverse drug reaction occurs vs. No pneumocystic carinii pneumonia PCP ; prophylaxis in patients with Wegener's Granulomatosis receiving immune suppressant therapy Trimethoprim-Sulfamethoxazole prophylaxis for pneumocystic carinii pneumonia PCP ; with switch to aerosolized pentamidine if adverse drug reaction occurs vs. TrimethoprimSulfamethoxazole prophylaxis with discontinuation if adverse drug reaction occurs in patients with Wegener's Granulomatosis receiving immune suppressant therapy Targeted preemptive once per week for cytomegalovirus CMV ; therapy vs. No cytomegalovirus CMV ; preemptive therapy in high risk HIV-infected patients identified by means of cytomegalovirus CMV ; polymerase chain reaction screening General cytomegalovirus CMV ; prophylaxis vs. Targeted preemptive cytomegalovirus CMV ; therapy in high risk HIV-infected patients identified by means of cytomegalovirus CMV ; polymerase chain reaction screening Pneumococcal vaccination for prevention of invasive pneumococcal disease and pneumococcal pneumonia vs. No pneumococcal vaccination in individuals aged 65 yrs. in Scotland Pneumococcal vaccination for prevention of invasive pneumococcal disease and pneumococcal pneumonia vs. No pneumococcal vaccination in individuals aged 65 yrs. in France Pneumococcal vaccination for prevention of invasive pneumococcal disease vs. No pneumococcal vaccination in individuals aged 65 yrs. in Spain Pneumococcal vaccination for prevention of invasive pneumococcal disease vs. No pneumococcal vaccination in individuals aged 65 yrs. in Scotland Pneumococcal vaccination for prevention of invasive pneumococcal disease vs. No pneumococcal vaccination in individuals aged 65 yrs. in France Pneumococcal vaccination for prevention of invasive pneumococcal disease vs. No pneumococcal vaccination in individuals aged 65 yrs. in Belgium Pneumococcal vaccination for prevention of invasive pneumococcal disease vs. No pneumococcal vaccination in individuals aged 65 yrs. in Sweden 140, 000 and
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The most common adverse reactions reported were infection, tremor, hypertension, decreased renal function, constipation, diarrhea, headache, abdominal pain and insomnia. Adverse events that occurred in 15% of Prograf-treated kidney transplant patients are presented below.
Medicure Inc. Medicure Inc. Medicure Inc. Mitsubishi Pharma Corp. Mitsubishi Pharma Corp. Mitsubishi Pharma Corp. Mitsubishi Pharma Corp. Mitsubishi Pharma Corp. Amarin Corp. plc MultiCell Technologies, Inc. MultiCell Technologies, Inc. MultiCell Technologies, Inc. MultiCell Technologies, Inc. Microbia, Inc. Microbia, Inc. Corixa Corp. BioNumerik Pharmaceuticals, Inc. BioNumerik Pharmaceuticals, Inc. Medical Discoveries, Inc. Aventis Pharma AG Idera Pharmaceuticals, Inc and
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El tipo de conservacin utilizada y la temperatura de almacenamiento. Tiempo de conservacin de rganos Corazn . horas Hgado . 1218 horas Riones 2448 horas Corazn-pulmones horas Pulmones . horas Pncreas 1218 horas Cumplimiento "Compliance" ; Acto de seguir rdenes, observar reglas y polticas. Ejemplo, tomar medicinas en la forma indicada. Drogas antirrechazo "Anti-rejection Drugs" ; Medicinas desarrolladas para suprimir la respuesta inmune y para que el cuerpo acepte, y no rechace, un rgano o tejido trasplantado. Estas medicinas tambin se llaman inmunosupresores. Enfermedad Renal en Etapa Final "End Stage Renal Disease", ESRD siglas en ingls ; Enfermedad Renal en Etapa Final o fallo crnico de los riones. Afeccin en que los riones dejan de funcionar y para la cual los pacientes necesitan dilisis o un trasplante. Estado puntaje Status score ; Cdigo o nmero usado para indicar el grado de urgencia mdica de los pacientes que esperan trasplantes de corazn, hgado, o pulmn. Injerto "Graft" ; rgano o tejido trasplantado. Inmunosupresor "Immunosuppressant" ; Medicamento utilizado despus del trasplante para prevenir que se rechace el rgano trasplantado, al suprimir el sistema de defensa del cuerpo. Los medicamentos ms usados son tacromilus Prograf, FK506 ; , cyclosporine Sandimmune, Neoral, Gengraf ; , prednisone Deltasone, genrico ; , azathioprine Imuran ; , basil.
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Word is that novartis is going to be the first to market with a generic tacrolimus just to stick it to usa size: 284 bytes customize: 1 progrraf started 1 week, 3 days ago : 00 ; by anonymous quote: originally posted by anonymous it' s true and
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Oc: cur I ; c: yo~itl I. 4.05. At 18.0 E * 13.0 ; , as w: increi~sep, at L lb * 4.8, the c region of tlie map for m a l values of x makes contact with the bisector giving rise to a fold bifurcation with the creation of a pair of stable and unstable fixed points, pz and pa Fig. 7.51 . Keeping E the bisector and the map gets progressively narrow, thereby stabilizing periodic orbits of higher periodicity See Fig. 7.3 and also Figs. 7.7a, 7.9a ; . The positions of the iterates of higher periodic cycles change marginally to accommodate the next higher periodic cycle as arl Iiti mi~1 it, erati?s itre sqlleezed in this intermittent channel. Thus, the intermittency or the fold l ; if~~rci~t, io~i p * ; is an accumulation point for the arithmetically i~icreasirlgperiod point atltliiig sequences. Beyond the acci~rnulationpoint, no further bifurcations are observed for.
Membership of the ceg clinical effectiveness group: chairman, keith radcliffe mssvd ; , imtyaz ahmad-jushuf agum ; , mark fitzgerald agum ; , janet wilson royal college of physicians gu medicine committee ; , jan welch mssvd.
International Reference Prices For both the core and supplementary lists of medicines, the Management Sciences for Health MSH ; Drug Price Indicator Guide 2005 prices were selected as the most useful standard. The MSH reference prices are the medians of recent procurement or tender prices offered predominantly by not-for-profit suppliers to developing countries for multisource products. When supplier prices were not available, buyer prices were used.
Those who are eligible for medicaid — which provides coverage to those with low income — also may be eligible for medicare, for example, p4ograf ipf5100.
Without big pharma, we would have no money and tacrolimus.
22. Zimmer L, Vancassel S, Cantagrel S, et al. The dopamine mesocorticolimbic pathway is affected by deficiency in n-3 polyunsaturated fatty acids. J Clin Nutr 2002; 75: 662667 Hibbeln JR, Bisette G, Umhau JC, et al. Omega-3 status and cerebrospinal fluid corticotrophin releasing hormone in perpetrators of domestic violence. Biol Psychiatry 2004; 56: 895897 Mirnikjoo B, Brown SE, Seung Kim HF, et al. Protein kinase inhibition by omega-3 fatty acids. J Biol Chem 2001; 276: 1088810896 Kinsella JE. Lipids, membrane receptors, and enzymes: effects of dietary fatty acids. JPEN J Parenter Enteral Nutr 1990; 14: S200S217 26. Villa B, Calabresi L, Chiesa G, et al. Omega-3 fatty acid ethyl esters increase heart rate variability in patients with coronary disease. Pharmacol Res 2002; 45: 475 Calderon F, Kim HY. Docosahexaenoic acid promotes neurite growth in hippocampal neurons. J Neurochem 2004; 90: 979988 Kim HY, Akbar M, Lau A. Effects of docosapentaenoic acid on neuronal apoptosis. Lipids 2003; 38: 453457 Tsukada H, Kakiuchi T, Fukumoto D, et al. Docosahexaenoic acid DHA ; improves the age-related impairment of the coupling mechanism between neuronal activation and functional cerebral blood flow response: a PET study in conscious monkeys. Brain Res 2000; 862: 180186 Wainwright PE. Dietary essential fatty acids and brain function: a developmental perspective on mechanisms. Proc Nutr Soc 2002; 61: 6169 Kitajka K, Puskas LG, Zvara A, et al. The role of n-3 polyunsaturated fatty acids in brain: modulation of rat brain gene expression by dietary n-3 fatty acids. Proc Natl Acad Sci U S A 2002; 99: 26192624 Hibbeln JR. Fish consumption and major depression [letter]. Lancet 1998; 351: 1213 Hibbeln JR. Seafood consumption, the DHA content of mothers' milk and prevalence rates of postpartum depression: a cross-national, ecological analysis. J Affect Disord 2002; 69: 1529 Noaghiul S, Hibbeln JR. Cross-national comparisons of seafood consumption and rates of bipolar disorders. J Psychiatry 2003; 160: 22222227 Hakkarainen R, Partonen T, Haukka J, et al. Is low dietary intake of omega-3 fatty acids associated with depression? J Psychiatry 2004; 161: 567569 Tanskanen A, Hibbeln JR, Hintikka J, et al. Fish consumption, depression and suicidality in a general population. Arch Gen Psychiatry 2001; 58: 512513 Tanskanen A, Hibbeln JR, Tuomilehto J, et al. Fish consumption and depressive symptoms in the general population in Finland. Psychiatr Serv 2001; 52: 529531 Silvers KM, Scott KM. Fish consumption and self-reported physical and mental health status. Public Health Nutr 2002; 5: 427431 Cott J, Hibbeln JR. Lack of seasonal mood change in Icelanders [letter]. J Psychiatry 2001; 158: 328 Christensen O, Christensen E. Fat consumption and schizophrenia. Acta Psychiatr Scand 1988; 78: 587591 Moriguchi T, Loewke J, Garrison M, et al. Reversal of docosahexaenoic acid deficiency in the rat brain, retina, liver, and serum. J Lipid Res 2001; 42: 419427 Guallar E, Aro A, Jimenez FJ, et al. Omega-3 fatty acids in adipose tissue and risk of myocardial infarction: the EURAMIC study. Arterioscler Thromb Vasc Biol 1999; 19: 11111118 Maes M, Smith RS, Christophe A, et al. Fatty acid composition in major depression: decreased omega 3 fractions in cholesteryl esters and increased C20: 4 omega 6 C20: 5 omega 3 ratio in cholesteryl esters and phospholipids. J Affect Disord 1996; 38: 3546 Adams PB, Lawson S, Sanigorski A, et al. Arachidonic acid to eicosapentaenoic acid ratio in blood correlates positively with clinical symptoms of depression. Lipids 1996; 31: S157S161 45. Edwards R, Peet M, Shay J, et al. Omega-3 polyunsaturated fatty acid levels in the diet and in red blood cell membranes of depressed patients. J Affect Disord 1998; 48: 149155 Peet M, Murphy B, Shay J, et al. Depletion of omega-3 fatty acid levels in red blood cell membranes of depressive patients. Biol Psychiatry 1998; 43: 315319 Mamalakis G, Kiriakakis M, Tsibinos G, et al. Depression and adipose polyunsaturated fatty acids in the survivors of the Seven Countries Study population of Crete. Prostaglandins Leukot Essent Fatty Acids 2004; 70: 495501 Tiemeier H, van Tuijl HR, Hofman A, et al. Plasma fatty acid composi.
Courtesy of NIHON ARUTU PHARMACEUTICAL CO., LTD. S930422D ; S930422G.
Most clinical trial protocols specified that the drug be taken immediately after meals.
I'll see if i can find it in drugstores in singapore.
Ajinomoto Co., Inc. Management Strategy Business Strategy Quality Assurance R&D Ajinomoto Medica Co., Ltd. Production and Distribution, because prograf ipf500.
Additionally, studies in adult kidney, adult liver, adult heart and pediatric liver transplant recipients have demonstrated continued maintenance of the efficacy and safety of milligram-to-milligram conversion of twice-daily prograf to once-daily prograf one of the studies presented today was the one-year follow-up results in pediatric liver transplant recipients converted from prograf to prograf recipients enrolled in the study were between the ages of five and 12 and were evaluated based on dosing and trough levels, laboratory values, concomitant medications, graft survival and adverse events.
C10H17N1. M: 151.25. Available commercially as the free base, or as the hydrochloride, sulfate or fumarate salts. Production: 1-bromoadamantane + acetonitrile Ritter reaction ; Derivatives: tromantadine Uses: antiviral antiparkinsonian drug amaranth See: Acid Red 27 ambazone [539-21-9].
Primary Reference Freeman et al. 150 ; Leitenberg et al. 141 ; Wolf and Crowther 144 ; Year of publication 1988 1992 Type of BT Individual Group Group EDI Data suitable for inclusion in quantitative analyses? Data suitable for inclusion in qualitative analysis? Outcome assessed but unusable?.
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1. Ettinger D. NCCN Practice Guidelines in Oncology - Antiemesis v.1.2004. NCCN, 7 August 2004. Accessed February 11, 2005. 2. Hoskins P. Antiemetic Guidelines. Vancouver: BCCA; October 2004. 3. Gralla R. Recommendations for the Use of Antiemetics: Evidence-Based, Clinical Practice Guidelines. Journal of Clinical Oncology 1999; 17 9 ; : 2971-94. 4. Hesketh PJ KM, Grunberg SM et al. Proposal for classifying the acute emetogenicity of cancer chemotherapy. Journal of Clinical Oncology 1997; 15: 103-9. Skeel RT, editor. Handbook of Cancer Chemotherapy. 6th ed. Philadelphia PA: Lippincott Williams & Wilkins; 2003. 6. ASHP. ASHP therapeutic guidelines on the pharmacologic management of nausea and vomiting in adult and pediatric patients receiving chemotherapy or radiation therapy or undergoing surgery. J Health-Syst Pharm 1999; 56 Apr 15 ; : 729-64. 7. Geling O, Eichler HG. Should 5-hydroxytryptamine-3 receptor antagonists be administered beyond 24 hours after chemotherapy to prevent delayed emesis? Systematic re-evaluation of clinical evidence and drug cost implications. J Clin Oncol 2005; 23 6 ; : 1289-94. 8. Culy CR, Spencer CM. Amifostine: an update on its clinical status as a cytoprotectant in patients with cancer receiving chemotherapy or radiotherapy and its potential therapeutic application in myelodysplastic syndrome. Drugs 2001; 61 5 ; : 641-84. 9. Repchinsky C, editor. Compendium of Pharmaceuticals and Specialties. Ottawa, Ontario, Canada: Canadian Pharmacists Association; 2003. 10. Mackean M, Planting A, Twelves C, et al. Phase I and pharmacologic study of intermittent twice-daily oral therapy with capecitabine in patients wit advanced and or metastatic cancer. Journal of Clinical Oncology 1998; 16: 2977-85. Bristol-Myers Squibb. Paraplatin-aq product monograph. Montreal, Quebec; 9 March 1994. 12. BCCA. Cancer Drug Manual. BCCA, 2005. Accessed 2005. 13. Aventis Pharma Inc. Taxotere product monograph. Saint-Laurent: Qubec; 26 April 1999. 14. Eli Lilly Canada. Gemzar product monograph. Toronto, Ontario; 19 August, 1999. 15. AstraZeneca, Canada. Iressa Product Monograph. Mississauga, Ontario; 2003. 16. Repchinsky C, editor. Compendium of Pharmaceuticals and Specialties. Ottawa, Ontario, Canada: Canadian Pharmacists Association; 2004. 17. McEvoy GK, editor. American Hospital Formulary Service. 2004 ed. Bethesda: American Society of Health-System Pharmacists Inc.; 2004. 18. Pharmacia and Upjohn. Camptosar product monograph. Mississauga, Ontario; 26 August 1999. 19. AstraZeneca. Tomudex product monograph. Canada Inc. Mississauga, Ontario; 2000. 20. Hoffmann-LaRoche. Rituxan product monograph. Mississauga, Ontario; 21 June, 2000. 21. Thiessen B. Personal communication. De Lemos M, editor. Vancouver; 2002. p. email discussion of temozolomide emetogenicity. 22. SmithKline Beecham Pharma. Hycamtin product monograph. Oakville, Ontario; 23 April 1999. 23. Glaxo Wellcome. Navelbine product monograph. Mississauga: Ontario; 29 October 1998.
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